The US has not manufactured thallium since 1984. Thallium is often imported for products like optical lenses and electronics. Thallium was an effective murder weapon before its effects became understood and an antidote ( Prussian blue) was discovered. However hair-loss generally occurs only with low doses with high doses the thallium kills before hair loss can occur. Thallium was originally used as rat poison, but was discontinued due to the exposure risk.Īmong the distinctive effects of thallium poisoning are peripheral nerve damage (victims may experience a sensation of “walking on hot coals”) and hair loss (which led to its initial use as a depilatory before its toxicity was properly appreciated). Thus this substitution disrupts many cellular processes by interfering with the function of proteins that incorporate cysteine, an amino acid containing sulfur. Other aspects of thallium's chemistry differ strongly from that of the alkali metals, such as its high affinity for sulfur ligands. It can thus enter the body via potassium uptake pathways. Part of the reason for thallium's high toxicity is that when present in aqueous solution as the univalent thallium(I) ion (Tl +) it exhibits some similarities with essential alkali metal cations, particularly potassium (owing to similar ionic radii). Exposure to them should not exceed 0.1 mg per m 2 of skin in an 8 hour time-weighted average (40- hour working week). Many thallium compounds are highly soluble in water and are readily absorbed through the skin. Contact with skin is dangerous and adequate ventilation should be provided when melting this metal. Thallium poisoning is poisoning that is due to thallium and its compounds, which are often highly toxic.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |